PDRN Cream: What the Labels and Prices Tell You

What a PDRN cream is for

A PDRN cream is marketed for moisturizing and skin recovery, but those promises are not established equally. Dr.Reju-All says its cream improves hydration, firmness and texture while supporting renewal and recovery. Dr Rachel Ho’s review suggests PDRN creams may serve as adjunct skincare for the moisture barrier and healing after peels or lasers. That is a cautious proposed role, not proof that every PDRN moisturizer delivers those effects.

Do not expect a cream to reproduce an injectable treatment. Dr Rachel Ho says salmon PDRN’s relatively large molecular weight limits absorption through intact skin, so injection results cannot be extrapolated to creams or serums. She also calls for controlled human trials to substantiate cream safety and efficacy. Our PDRN research guide helps keep those evidence questions separate. For post-procedure use or a skin condition, ask a board-certified dermatologist rather than relying on a recovery claim.

Sources: [9] [11]

What is on the market

The official US store records include creams, a gel, balms and a tinted moisturizer—not a single uniform format. The mixsoon store lists mixsoon PDRN Collagen Cream 50ml and mixsoon PDRN Collagen Tinted Moisturizer | All 10 Shades. VT Cosmetics lists VT Cosmetics PDRN Capsule Cream, VT Cosmetics PDRN Cream 100 and VT Cosmetics PDRN STICK BALM. These are store product names, not independent descriptions of texture or performance.

medicube’s listed range includes medicube PDRN Booster Gel, medicube PDRN Pink Collagen Volume Multi Balm, medicube PDRN Pink Collagen Capsule Cream, medicube PDRN Pink Peptide Cream and medicube PDRN Collagen Gua Sha Neck Wrinkle Cream. The selection therefore extends beyond products named simply “cream.” For a closer look at the balm listing, see our medicube stick guide; the format name alone does not establish how it feels on skin.

The remaining records cover Dr.Reju-All Advanced PDRN Rejuvenating Cream, Mediheal Derma Cream PDRN Lifting, Genabelle PDRN Rejuvenating Cream 70ml, Genabelle PDRN Enriched Recovery Balm, Anua PDRN Hyaluronic Acid 100 Moisturizing Cream and Centellian24 Expert Madeca Cream Active Renew PDRN 50ml. The comparison table uses official store data checked October 8, 2026. Marketplace listings were also found, but their prices and sellers were not checked.

Sources: [1] [2] [3] [4] [5] [6] [7] [8]

PDRN amounts on labels

The PDRN amounts quoted here are brand-reported concentrations, not independently verified measurements. VT Cosmetics states 100,000ppm for PDRN Capsule Cream; Centellian24 states 20,000ppm for Expert Madeca Cream Active Renew PDRN 50ml; Genabelle states 5,000ppm for PDRN Enriched Recovery Balm; and Dr.Reju-All states 1,200 ppm for Advanced PDRN Rejuvenating Cream. We have not tested these amounts, and a concentration-based ranking of results is not established.

A brand’s explanation of its chosen amount remains a claim. Dr.Reju-All describes 1,200 ppm as optimal based on its absorption and safety reasoning, and identifies its PDRN as salmon DNA with claimed 99% purity. Those statements do not resolve Dr Rachel Ho’s concerns about absorption or the need for controlled cream trials. Our Dr.Reju-All cream guide separates the product’s claims from the evidence limits.

Sources: [2] [4] [6] [8] [9] [11]

Prices and sizes

The listed cream prices run from $17.50 to $36.86 before including Dr.Reju-All’s larger $64.90 option. At the checked date, mixsoon’s cream was $17.50 for 50 ml, Mediheal’s was $23.00 for 50 ml, and Anua’s was $31.00 for 60 ml. VT Cosmetics PDRN Cream 100 was $36.86, but its size is not included in these records. These are official US store prices, not verified marketplace offers.

Package size changes what a price comparison tells you. Dr.Reju-All lists $22.90 for 20 ml and $64.90 for 60 ml; Genabelle’s cream is $25.00 for 70 ml. medicube lists its capsule cream at $26.00 for 55 g and its peptide cream at $26.00 for 50 ml. The records use both grams and milliliters, so this page does not treat those quantities as interchangeable.

Sources: [1] [2] [3] [5] [6] [7] [9]

How to choose

Choose by the information you can verify, rather than by a claimed PDRN amount alone. The store records let you compare product format, listed size and price. For a PDRN balm or PDRN stick, VT Cosmetics lists its stick balm at $18.43, medicube lists its multi balm at $22.00, and Genabelle lists its recovery balm at $29.00 for 50 ml. Sizes are not included here for the other balm listings.

Read the rest of the formula and keep marketing terms in their proper place. Dr.Reju-All lists niacinamide, panthenol, sodium hyaluronate, hydrolyzed collagen, sodium DNA and adenosine among its ingredients. It also describes the cream as dermatologically tested and non-irritating, but that is the brand’s statement, not evidence of how your skin will respond. A winner for sensitivity, acne scars or wrinkles is not established; discuss allergies or skin conditions with a board-certified dermatologist.

Sources: [2] [3] [6] [9] [11]

How to use it

Follow the specific product’s directions; the cream instructions quoted here come from Dr.Reju-All. The brand says to apply its cream after cleansing in morning and evening routines, across the face or on targeted areas. It says the cream can replace a serum or emulsion and recommends an extra layer on dry areas at night. Those directions belong to that product and should not be presented as instructions for every cream, gel or balm.

Serum layering advice is not automatically cream advice. The INKEY List tells users to apply its PDRN Serum after cleansing, followed by moisturizer and morning sunscreen; our PDRN serum guide covers that separate format. Dr.Reju-All advises patch testing its cream. If you are pregnant, managing a skin condition or using it after a procedure, consult a board-certified dermatologist before treating brand instructions as a suitable personal routine.

Sources: [9] [10] [11]