By format
PDRN Serum: What the Label Can Tell You
A guide to the PDRN serums and ampoules we track in official US stores: what brands disclose, what bottles cost, and why a concentration claim is not a result.
By the PDRN Today desk · Updated Oct 9, 2026 · 13 sources · Not medical advice
PDRN serums and ampoules: 22 products, store prices
Prices from the official US brand stores, checked Oct 8, 2026. “View” buttons are affiliate links: we may earn a commission at no cost to you. We did not test these products; the order is by format and price, not a ranking.
| Product | Size | Store price | PDRN on label | Store link |
|---|---|---|---|---|
 Dr.Reju-AllAdvanced PDRN Copper Peptide Serumlabel states 1,200 ppm PDRN (brand claim) · also listed at Amazon, Ulta, Stylevana · brand copy mentions moisture or the skin barrier | 30 ml | $24.90$8.30 per 10 ml | 1,200 ppm | View |
 VT CosmeticsPDRN Essence 100label states 100,000 ppm PDRN (brand claim) · also listed at Amazon, Ulta · brand copy mentions moisture or the skin barrier | not listed | $34.56 | 100,000 ppm | View |
 Centellian24PDRN Firming Boosting ampoule 30mllabel states 300,000 ppm PDRN (brand claim) · also listed at YesStyle, Olive Young Global | 30 ml | $35.00$11.67 per 10 ml | 300,000 ppm | View |
| Product | Size | Store price | PDRN on label | Store link |
|---|---|---|---|---|
| mixsoonPDRN Collagen Retinal 6 Capsule Serum 30ml | 30 ml | $15.40$5.13 per 10 ml | not stated | View |
| mixsoonPDRN Collagen Serum 30ml | 30 ml | $16.10$5.37 per 10 ml | not stated | View |
| VT CosmeticsPDRN R5 Firming Ampoule | 30 ml | $18.00$6.00 per 10 ml | not stated | View |
 MedihealPDRN Lifting Serum | 40 ml | $18.70$4.67 per 10 ml | not stated | View |
 medicubePDRN Pink One Day Serum | not listed | $19.00 | not stated | View |
| medicubeUltra Light PDRN Pink Peptide Serum | 30 ml | $21.00$7.00 per 10 ml | not stated | View |
| medicubePDRN Pink Collagen Exosome Shot | not listed | $22.00 | not stated | View |
| GenabellePDRN Vita Toning Ampoule | 30 ml | $22.50$7.50 per 10 ml | 20,000 ppm | View |
| VT CosmeticsPDRN GLOW AMPOULE | not listed | $23.04 | not stated | View |
| medicubePDRN Pink Collagen Glow Jelly Serum | 30 ml | $24.00$8.00 per 10 ml | not stated | View |
| medicubePDRN Pink Collagen Bubble Serum | 95 ml | $24.00$2.53 per 10 ml | not stated | View |
| medicubeHyaluronic Multi Peptide PDRN Serum | 30 ml | $24.00$8.00 per 10 ml | not stated | View |
| medicubePDRN Pink Peptide Serum | 30 ml | $24.00$8.00 per 10 ml | not stated | View |
| Dr.Reju-AllAdvanced PDRN Copper Peptide Serum | 30 ml | $24.90$8.30 per 10 ml | 1,200 ppm | View |
 AnuaPDRN Hyaluronic Acid Capsule 100 One Day Serum | not listed | $25.00 | not stated | View |
| GenabellePDRN 3% Hyper Boost Ampoule | not listed | $28.00 | 30,000 ppm | View |
| AnuaPDRN Hyaluronic Acid Capsule 100 Serum | 30 ml | $30.00$10.00 per 10 ml | not stated | View |
| VT CosmeticsPDRN Essence 100 | not listed | $34.56 | 100,000 ppm | View |
| Centellian24PDRN Firming Boosting ampoule 30ml | 30 ml | $35.00$11.67 per 10 ml | 300,000 ppm | View |
| Centellian24360º Shot PDRN Active Serum 50ml | 50 ml | $36.10$7.22 per 10 ml | not stated | View |
 innisfreeRetinol Green Tea PDRN™ Firming Serum | 25 ml | $37.00$14.80 per 10 ml | not stated | View |
| VT CosmeticsPDRN REEDLE SHOT 100 | not listed | $44.54 | not stated | View |
In brief
- Topical PDRN evidence does not establish results equivalent to injections.
- Disclosed PDRN amounts are source claims, not measurements we verified.
- Tracked serums and ampoules cost $15.40–$37.00 on October 8, 2026.
- Our selection rules consider amount disclosure, retailer listings and price—not a single winner.
What a PDRN serum is for
A PDRN serum is a topical skincare format marketed for concerns such as dryness, dullness and uneven skin; those targets are not established outcomes for every bottle. medicube lists these concerns for its PDRN Pink Peptide Serum. ELLE identifies PDRN as polydeoxyribonucleotide, while Dermatology Times describes it as purified DNA fragments. Our PDRN explainer covers the ingredient separately from the format.
Hydration and skin comfort are more cautious expectations than deep tissue repair. In Glamour, Dr. Christine Hall says PDRN facial serums can improve hydration, texture and comfort. Dermatology Times suggests that benefits may come largely from accompanying ingredients, with topical PDRN itself potentially providing modest surface hydration rather than the regenerative effects documented for injections.
Topical PDRN serum benefits remain less established than the marketing can suggest. Dermatology Times reports a small study of topical peony PDRN but cautions that its formulation does not represent most marketed products. The article also says claims equating serums with injectable procedures are unsupported. That distinction matters when a product page borrows the language of medical tissue repair.
What is on the market
The market table covers the serums and ampoules tracked in the official US stores of mixsoon, VT Cosmetics, Mediheal, medicube, Genabelle, Dr.Reju-All, Anua, Centellian24 and innisfree. Prices reflect the October 8, 2026 check, not a promise about checkout today. The broader product directory separates this format from other PDRN skincare.
Names describe different product presentations, not a demonstrated hierarchy of performance. The stores list products including VT Cosmetics PDRN R5 Firming Ampoule, Mediheal PDRN Lifting Serum and medicube PDRN Pink Collagen Bubble Serum. These listings establish the names, prices and available sizes. They do not establish that an ampoule delivers stronger effects than a serum.
Retailer availability is a listing check, not a seller audit. Searches found Dr.Reju-All Advanced PDRN Copper Peptide Serum at Amazon, Ulta and Stylevana, and Anua PDRN Hyaluronic Acid Capsule 100 Serum at Amazon, Ulta and YesStyle. Those checks did not verify the sellers or their prices, so the table uses official-store pricing rather than marketplace offers.
From the table above: The Dr.Reju-All Advanced PDRN Copper Peptide Serum is $24.90 for 30 ml at the Dr.Reju-All store (checked Oct 2026). See it at the store · affiliate link · or browse all 20 products.
PDRN amounts on labels
A disclosed PDRN amount is a brand claim, not a measurement we verified. Dr.Reju-All states that Advanced PDRN Copper Peptide Serum contains 1,200 ppm PDRN. Genabelle states that Genabelle PDRN Vita Toning Ampoule contains 20,000ppm, while PDRN 3% Hyper Boost Ampoule contains 30,000ppm. Preserve those distinctions when comparing labels rather than treating the product name alone as a complete concentration statement.
A larger printed amount does not establish a better topical result. Centellian24 states that PDRN Firming Boosting ampoule 30ml contains 300,000 ppm PDRN. That claim describes quantity, not proven delivery or effectiveness. Dermatology Times says most brands do not disclose molecular weight, encapsulation methods or in vivo evidence of delivery into the dermis; our research guide keeps those questions separate.
Ingredient origin also needs checking rather than guessing from the category. medicube lists salmon DNA PDRN and vegan Rose PDRN as ingredient options for its serum. ELLE quotes Dr. Derrick Phillips recommending formulas that disclose quantity and origin. If you want a salmon PDRN serum specifically, verify the selected option; equivalent results from different origins are not established.
Prices and sizes
The tracked products named as serums or ampoules span $15.40–$37.00 in official US stores on October 8, 2026. At the lower end, mixsoon PDRN Collagen Retinal 6 Capsule Serum 30ml was $15.40 for 30 ml. At the upper end, innisfree Retinol Green Tea PDRN™ Firming Serum was $37.00 for 25 ml. This is a price spread, not an effectiveness ranking.
Bottle sizes change what the shelf price tells you. Mediheal PDRN Lifting Serum was $18.70 for 40 ml, while medicube PDRN Pink Collagen Bubble Serum was $24.00 for 95 ml. Centellian24 360º Shot PDRN Active Serum 50ml was $36.10 for 50 ml. Where the checked store record does not establish a size, leave it unknown rather than borrowing another product's volume.
Discounts are part of the dated record, not permanent prices. The mixsoon serum was marked down from $22.00, and Centellian24 360º Shot PDRN Active Serum 50ml was marked down from $38.00. Anua PDRN Hyaluronic Acid Capsule 100 Serum was listed at $30.00 for 30 ml, with no markdown recorded at the check. Check the current official listing before paying.
How to choose—and how we pick serums
Our picks use disclosed PDRN amount, listings at several major retailers and price as selection rules—not skin-testing scores. The picks table applies those rules to the checked records. A product without an established amount in those records may appear in the market table without qualifying for a pick. Disclosure and availability make comparison easier; neither proves performance.
Choose around the whole formula and the concern you want to address. medicube lists PDRN Pink Peptide Serum for dry and combination skin, with salmon DNA PDRN, peptide and niacinamide as key ingredients. Those are brand descriptions, not a personal suitability assessment. In ELLE, Dr. Phillips advises breakout-prone shoppers to assess the entire formula because richer serums may not suit every skin type.
Do not use PDRN quantity as a reason to replace an established treatment. Dr. Phillips describes PDRN as a promising addition rather than a replacement for retinoids, and says topical evidence is still developing. Our PDRN and retinol comparison addresses that distinction. For prescription treatments, skin conditions or allergy concerns, discuss your choice with a board-certified dermatologist.
How to use it
A universal application order, dose or frequency for PDRN serums is not established by the sources cited here. Use the directions for the specific product rather than treating the ingredient name as a routine instruction. Our PDRN serum routine guide covers the questions to check. A serum name alone does not establish compatibility with everything already in your routine.
After a procedure, your practitioner's instructions take priority over a general skincare routine. In ELLE, Dr. Phillips says PDRN may be useful after laser or microneedling but advises following practitioner aftercare guidance before introducing active skincare. Ask your treating board-certified dermatologist or licensed injector when to introduce a product; these sources do not establish a universal waiting period.
A brand's timeline or irritation claim does not establish how your skin will respond. medicube says visible improvements with its serum can occur in as little as two weeks, while acknowledging that individual results vary. It also describes the serum as tested to be low-irritating. Those claims do not establish that the product will suit you; consult a board-certified dermatologist about allergies or skin conditions.
Questions readers ask
What is PDRN serum?
PDRN serum is topical skincare containing an ingredient identified by ELLE as polydeoxyribonucleotide. Dermatology Times describes PDRN as purified DNA fragments and discusses newer plant-derived or fermentation-derived versions. The format is cosmetic skincare, not an injection, and the article says claims that topical serums equal injectable procedures are unsupported.
Does PDRN serum actually work?
The evidence does not establish injection-like results for commercial PDRN serums. Dermatology Times reports a small topical peony PDRN study but says that formulation is not representative of most marketed products. It suggests serum benefits may come from accompanying ingredients, with PDRN itself potentially offering modest surface hydration and superficial anti-inflammatory signaling.
Is all PDRN serum made from salmon DNA?
No: the sources describe alternatives as well as salmon-derived PDRN. Dermatology Times discusses plant-derived and fermentation-derived versions, while medicube lists salmon DNA PDRN and vegan Rose PDRN options. Check the specific option and origin disclosure. If you have a fish allergy, consult a board-certified dermatologist rather than assuming a topical product is suitable.
Can PDRN serum replace retinol?
The evidence cited here does not support replacing retinol with PDRN serum. In ELLE, Dr. Derrick Phillips describes PDRN as a promising addition to an anti-aging routine rather than a replacement for retinoids. He also says topical evidence is still developing and PDRN should not replace established treatments. Discuss changes to prescription treatment with a board-certified dermatologist.
Sources (13)Every fact on this page comes from these documents
Checked on the date shown. Brand and clinic statements are their claims, not our findings. Studies carry their PubMed ID.
- mixsoon US store · mixsoon official store (US): PDRN products, prices checked 2026-10-08
- VT Cosmetics global store · VT Cosmetics official store (US): PDRN products, prices checked 2026-10-08
- Mediheal store · Mediheal official store (US): PDRN products, prices checked 2026-10-08
- medicube US store · medicube official store (US): PDRN products, prices checked 2026-10-08
- Genabelle store · Genabelle official store (US): PDRN products, prices checked 2026-10-08
- Dr.Reju-All store · Dr.Reju-All official store (US): PDRN products, prices checked 2026-10-08
- Anua US store · Anua official store (US): PDRN products, prices checked 2026-10-08
- Centellian24 store · Centellian24 official store (US): PDRN products, prices checked 2026-10-08
- innisfree US store · innisfree official store (US): PDRN products, prices checked 2026-10-08
- medicube US store · PDRN Pink Peptide Serum
- glamour.com · 7 Best K-Beauty PDRN Serums We Tested for Brighter, More Resilient Skin
- elle.com · PDRN Serums Are The Secret To Glass Skin: 6 Of The Best New Products To Boost Collagen
- dermatologytimes.com · Social Media Mythbusters: PDRN Serums
Information only, not medical advice. Product claims are the brands’ own. For injections, prescription treatments, pregnancy or a skin condition, talk to a board-certified dermatologist. How this site works.